Reveal what other systems miss

Understand nanoparticle populations with greater clarity using NanoSight Pro - the most widely cited nanoparticle tracking analysis platform in biomaterials and pharmaceutical research.

Reveal What Other Systems Miss

NanoSight Pro from Malvern Panalytical delivers high-resolution Nanoparticle Tracking Analysis, enabling scientists to measure particle size and concentration at the individual particle level across biologics, vaccines and advanced drug delivery systems. It transforms how nanoparticle populations are understood, replacing averaged assumptions with direct visualisation and precise measurements.

By tracking and analysing each particle in real time, NanoSight reveals heterogeneity, aggregation and subtle concentration changes that traditional techniques overlook. This provides a more complete and reliable understanding of complex biologic samples, supporting confident decision-making from early research through to quality control.

Built on decades of leadership in particle characterisation, NanoSight is trusted globally to deliver the clarity and reproducibility scientists need to advance development, reduce risk and meet regulatory expectations.


The challenge of measuring particle size in biologics and pharmaceuticals

In many labs, particle characterisation still relies on bulk measurement techniques that present a simplified view of highly complex systems. A single averaged result can appear clean and reassuring, but it rarely reflects reality.

Biologic samples are inherently heterogeneous and dynamic. Within one sample, multiple particle populations can coexist, each behaving differently and evolving over time. Early-stage aggregation may begin to form. Subtle shifts in concentration can emerge. Rare particles, often invisible to bulk techniques, may carry significant implications. When these signals are averaged, they disappear.

This creates a false sense of confidence. Important variations are masked. Critical insights are missed. And decisions are made on data that does not fully represent the sample.

These are not edge cases. They are everyday challenges in biologics, vaccines and drug delivery research. And they directly influence outcomes such as stability, efficacy and safety.

With NanoSight you can:

  • Measure and visualise individual particles rather than relying on averages
  • Identify multiple particle populations within a single sample
  • Detect early-stage aggregation and subtle changes in concentration
  • Reveal rare particles that can impact safety and efficacy
  • Understand true particle size distribution for more confident decisions

A clearer way to see and understand with NanoSight

NanoSight changes the way nanoparticles are measured and understood. As the established standard in Nanoparticle Tracking Analysis, it enables scientists to visualise and analyse particles individually rather than relying on averaged assumptions. Each particle is tracked, measured and counted in real time, delivering a direct and detailed view of your sample.

This approach provides both size and concentration data in a single measurement, allowing you to build a complete and reliable picture without the need for multiple techniques.

By observing particles individually, you can distinguish between populations, detect rare events and uncover subtle changes that would otherwise remain hidden.

With NanoSight you can:

Measure size and concentration together

Detect rare and subtle particle populations

Visualise particles individually

Track changes and movement over time

Without reliable analytical data, teams risk delayed development, failed formulations and challenges during scale-up and approval.

Through reproducibility of robust data insights, NanoSight allows you to measure and understand samples with absolute confidence

From real-world conditions to real impact

Biologic samples rarely behave under ideal conditions. They are often low in concentration, sensitive to handling and embedded in complex, biologically relevant matrices. Many measurement systems struggle in these environments, producing inconsistent or incomplete data that is difficult to rely on.

NanoSight is engineered to deliver clarity under real-world conditions. It performs reliably in challenging buffers and complex samples, maintaining consistency across users, labs and workflows. This reproducibility ensures that data can be trusted, whether in early research or regulated environments.

With NanoSight, this level of insight and clarity extends across the entire biologics pipeline:

  • Early discovery
    Understand particle behaviour and screen candidates with greater precision
  • Formulation development
    Optimise stability and performance by identifying aggregation and variability early
  • Process development
    Maintain control and consistency as you scale
  • Quality control
    Generate robust, reproducible measurements that support regulatory expectations

At every stage, clearer nanoparticle insight leads to better decisions. It reduces uncertainty, strengthens data packages and supports confident progression through development.

 
 

Explore how Nanosight Pro is enabling the development of biologics and pharmaceutical innovations.  

Why NanoSight?

The Malvern Panalytical NanoSight Pro is powered by decades of innovation from the leaders in Nanoparticle Tracking Analysis (NTA) – no wonder it’s the most widely cited NTA solution in peer-reviewed biomaterials research. Why settle for anything else, when you can choose NanoSight Pro?

  • Industry-leading NTA technology for precise particle size 
  • Reliable and reproducible particle measurements to predict and control formulation stability
  • Sensitive detection of concentration and fluorescence in biologics
  • Fast, reproducible results for R&D, QC and GMP environments
  • Trusted globally across biologics, vaccines and pharmaceutical development

Trusted by industry leaders

Across pharmaceutical innovation, nanoparticle research, drug manufacturing and quality control and assurance, scientists rely on NanoSight to deliver accurate, reproducible and trusted data; because when your samples define performance, you need results you can rely on. 

It basically makes the new user as expert as those of us who developed the technique. So, you are going to generate the same quality data at the push of a button.”

Bob Carr — Inventor of NTA technology