Measure size and concentration together

Understand nanoparticle populations with greater clarity using NanoSight Pro - the most widely cited nanoparticle tracking analysis platform in biomaterials and pharmaceutical research.

By tracking and analysing each particle in real time, NanoSight reveals heterogeneity, aggregation and subtle concentration changes that traditional techniques overlook. This provides a more complete and reliable understanding of complex biologic samples, supporting confident decision-making from early research through to quality control.
Built on decades of leadership in particle characterisation, NanoSight is trusted globally to deliver the clarity and reproducibility scientists need to advance development, reduce risk and meet regulatory expectations.
In many labs, particle characterisation still relies on bulk measurement techniques that present a simplified view of highly complex systems. A single averaged result can appear clean and reassuring, but it rarely reflects reality.
Biologic samples are inherently heterogeneous and dynamic. Within one sample, multiple particle populations can coexist, each behaving differently and evolving over time. Early-stage aggregation may begin to form. Subtle shifts in concentration can emerge. Rare particles, often invisible to bulk techniques, may carry significant implications. When these signals are averaged, they disappear.
This creates a false sense of confidence. Important variations are masked. Critical insights are missed. And decisions are made on data that does not fully represent the sample.
These are not edge cases. They are everyday challenges in biologics, vaccines and drug delivery research. And they directly influence outcomes such as stability, efficacy and safety.
With NanoSight you can:
NanoSight changes the way nanoparticles are measured and understood. As the established standard in Nanoparticle Tracking Analysis, it enables scientists to visualise and analyse particles individually rather than relying on averaged assumptions. Each particle is tracked, measured and counted in real time, delivering a direct and detailed view of your sample.
This approach provides both size and concentration data in a single measurement, allowing you to build a complete and reliable picture without the need for multiple techniques.
By observing particles individually, you can distinguish between populations, detect rare events and uncover subtle changes that would otherwise remain hidden.
With NanoSight you can:




Without reliable analytical data, teams risk delayed development, failed formulations and challenges during scale-up and approval.
Through reproducibility of robust data insights, NanoSight allows you to measure and understand samples with absolute confidence
Biologic samples rarely behave under ideal conditions. They are often low in concentration, sensitive to handling and embedded in complex, biologically relevant matrices. Many measurement systems struggle in these environments, producing inconsistent or incomplete data that is difficult to rely on.
NanoSight is engineered to deliver clarity under real-world conditions. It performs reliably in challenging buffers and complex samples, maintaining consistency across users, labs and workflows. This reproducibility ensures that data can be trusted, whether in early research or regulated environments.
With NanoSight, this level of insight and clarity extends across the entire biologics pipeline:
At every stage, clearer nanoparticle insight leads to better decisions. It reduces uncertainty, strengthens data packages and supports confident progression through development.

Analyse ADC heterogeneity and stability with NanoSight Pro. Detect aggregation early and optimise conjugation with particle-level insight.

Characterise extracellular vesicles in cell therapy. Gain nanoscale insight into cell health, potency, and consistency with NanoSight Pro.

Analyse extracellular vesicles with precision using NanoSight Pro. Detect heterogeneity, quantify particles, and de-risk exosome development. Gain reproducible insight into vesicle behaviour in solution.

Characterise viral vectors with precision using NanoSight Pro. Measure size, concentration, and aggregation to support gene therapy development.

Characterize lipid nanoparticles with precision using NanoSight Pro to optimise delivery, stability, and performance in biopharma development.

Detect protein aggregation early with NanoSight Pro. Gain particle-level insight to improve stability, reduce risk, and accelerate biologics development.

Characterise nanomedicine particles with precision using NanoSight Pro. Improve stability, targeting, and development outcomes.

Discover how NanoSight Pro supports Quality Control and Quality Assurance by delivering reliable, reproducible data for regulatory compliant biologics and pharmaceutical development and manufacturing.

Gain reproducible insight into particle and molecular behaviour in vaccine systems. Detect instability, optimise formulations and accelerate vaccine development with Zetasizer.
The Malvern Panalytical NanoSight Pro is powered by decades of innovation from the leaders in Nanoparticle Tracking Analysis (NTA) – no wonder it’s the most widely cited NTA solution in peer-reviewed biomaterials research. Why settle for anything else, when you can choose NanoSight Pro?

Across pharmaceutical innovation, nanoparticle research, drug manufacturing and quality control and assurance, scientists rely on NanoSight to deliver accurate, reproducible and trusted data; because when your samples define performance, you need results you can rely on.
It basically makes the new user as expert as those of us who developed the technique. So, you are going to generate the same quality data at the push of a button.”
Bob Carr — Inventor of NTA technology