How 2bind accelerates hit validation with GCI

Screen an entire kinase inhibitor library in 1 week

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Kinetics expert, Dr. Thomas Schubert will present how using the model system P38 to demonstrate a screening application of waveRAPID, using a library of kinase inhibitors. With waveRAPID, 2bind is now able to efficiently screen 1000s of molecules for binding kinetics and affinity.

Dr. Thomas Schubert, CEO from 2bind, is presenting data on how they use the Creoptix WAVE and recently launched waveRAPID method for their customer projects. During the virtual expert talk the following topics will be covered: 

  • The use of Grating-coupled Interferometry technology (GCI) at 2bind
  • Explanation of Multicycle Kinetics (MCK) versus waveRAPID® method 
  • Showcase of waveRAPID screening using the model system p38
  • Summary of the p38 screening results including recommendations
 

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WAVEsystem

Next-generation bioanalytical instruments for drug discovery and life sciences for both industry and academic research

The WAVEsystem, a Creoptix GCI Technology, puts a breakthrough level of binding kinetics analysis at your fingertips by pushing the boundaries of affinity range and sample compatibility. The WAVE's exceptionally high data quality, sample compatibility and automated software facilitates drug discovery and enable new inroads into R&D.

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