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Hot off the press – substrate interaction analysis
Recently we have enjoyed reading this new paper on substrate binding mechanisms.
Experiments were carried out to verify substrate binding, estimate binding affinities, and solve crystal structures with help from our PEAQ-ITC.
How to analyse GPCRs in less than 1 hour
G protein-coupled receptors (GPCRs) are fiendishly difficult to analyze because of their instability outside the cell membrane.
Our GPCRs technical note explains how with GCI you no longer need to rely on the 10 typical steps in GPCR purification. Work directly with crude or semi-purified samples using WAVEsystem. Bringing the whole process to under 1 hour in total.